Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction

Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction

Bibliographic Details
Main Author: Ithurburn, Matthew P.
Language:English
Published: The Ohio State University / OhioLINK 2017
Subjects:
Biomechanics
Biomedical Research
Health Sciences
Physical Therapy
Radiology
Rehabilitation
Sports Medicine
anterior cruciate ligament reconstruction
patient-reported function
knee mechanics
longitudinal outcomes
magnetic resonance imaging
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=osu1503059931724191
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-osu15030599317241912021-08-03T07:03:57Z Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction Ithurburn, Matthew P. Biomechanics Biomedical Research Health Sciences Physical Therapy Radiology Rehabilitation Sports Medicine anterior cruciate ligament reconstruction patient-reported function knee mechanics longitudinal outcomes magnetic resonance imaging Anterior cruciate ligament (ACL) ruptures are devastating injuries that occur frequently in young athletes, and ACL reconstruction (ACLR) is the typical treatment approach to restore knee ligamentous stability and allow for return to participation in sports. As a result of injury and ACLR, musculoskeletal impairments are commonly present during rehabilitation as well as at the time of return-to-sport (RTS). These impairments often include decreased muscle strength, knee anterior laxity, decreased knee range of motion, and the presence of a knee effusion. In addition, over time after ACLR, several negative sequelae associated with ACLR are reported. Indeed, large proportions of individuals demonstrate suboptimal patient-reported knee function 2 years after ACLR. Additionally, altered knee mechanics in individuals after ACLR are commonly identified during sport-related jumping and landing tasks, and these alterations often persist 2 years after surgery. Perhaps most concerning, individuals after ACLR also consistently develop premature knee osteoarthritis in the long term, and signs of early cartilage degeneration are identified using quantitative magnetic resonance imaging as early as 1 to 2 years after ACLR. However, currently, most negative sequelae associated with ACLR are evaluated at individual time points after ACLR, and not tracked over time, particularly in the young, active population. Additionally, there is not a comprehensive understanding of how impairment-level factors at the time of RTS after ACLR contribute to patient-reported knee function and landing mechanics over time, and in turn, how patient-reported knee function and landing mechanics are associated with early knee cartilage degeneration. This dissertation addresses these knowledge gaps in a series of studies. Chapter 1 reviews relevant background information from the literature, outlines important knowledge gaps to be addressed, as well as describes the overall study design for this dissertation. Chapters 2 through 4 examine how patient-reported function and landing symmetry change over the 2 years post-RTS after ACLR, and identify the impact of baseline (time of RTS) impairments and surgical and demographic factors on patient-reported function and landing symmetry over the subsequent 2 years. Chapters 5 through 7 then examine the associations between patient-reported knee function and landing symmetry over the 2 years post-RTS and knee cartilage integrity at 5 years post-RTS in a sub-group of young athletes after ACLR from the same cohort. Finally, Chapter 8 summarizes the contributions of this dissertation and offers suggestions for future research to be conducted.To our knowledge, the series of studies included in this dissertation represent the first to comprehensively evaluate the longitudinal relationships among knee-related musculoskeletal impairments, patient-reported function, landing mechanics, and knee cartilage integrity in a cohort of young athletes after ACLR. 2017 English text The Ohio State University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=osu1503059931724191 http://rave.ohiolink.edu/etdc/view?acc_num=osu1503059931724191 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Biomechanics
Biomedical Research
Health Sciences
Physical Therapy
Radiology
Rehabilitation
Sports Medicine
anterior cruciate ligament reconstruction
patient-reported function
knee mechanics
longitudinal outcomes
magnetic resonance imaging
spellingShingle Biomechanics
Biomedical Research
Health Sciences
Physical Therapy
Radiology
Rehabilitation
Sports Medicine
anterior cruciate ligament reconstruction
patient-reported function
knee mechanics
longitudinal outcomes
magnetic resonance imaging
Ithurburn, Matthew P.
Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction
author Ithurburn, Matthew P.
author_facet Ithurburn, Matthew P.
author_sort Ithurburn, Matthew P.
title Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction
title_short Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction
title_full Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction
title_fullStr Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction
title_full_unstemmed Associations among Knee Impairments, Patient-Reported Function, Landing Mechanics, and Knee Cartilage Integrity over Time after Anterior Cruciate Ligament Reconstruction
title_sort associations among knee impairments, patient-reported function, landing mechanics, and knee cartilage integrity over time after anterior cruciate ligament reconstruction
publisher The Ohio State University / OhioLINK
publishDate 2017
url http://rave.ohiolink.edu/etdc/view?acc_num=osu1503059931724191
work_keys_str_mv AT ithurburnmatthewp associationsamongkneeimpairmentspatientreportedfunctionlandingmechanicsandkneecartilageintegrityovertimeafteranteriorcruciateligamentreconstruction
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