The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers
| Main Author: | |
|---|---|
| Language: | English |
| Published: |
The Ohio State University / OhioLINK
2016
|
| Subjects: | |
| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=osu1459588788 |
| id |
ndltd-OhioLink-oai-etd.ohiolink.edu-osu1459588788 |
|---|---|
| record_format |
oai_dc |
| spelling |
ndltd-OhioLink-oai-etd.ohiolink.edu-osu14595887882021-08-03T06:35:19Z The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers Puski, Athena Joy Bowen Genetics Health Care Health Care Management BRCA1 BRCA2 HBOC management decision-making risk-reduction risk-reducing surgery surgical decision screening decision surveillance decision ease of decision-making physician doctor genetic counselor decision-making factors Women with a <i>BRCA1</i> or <i>BRCA2</i> mutation have a 40-74% breast cancer risk and 11-46% ovarian cancer risk by age 70. Due to this elevated risk, it is recommended that mutation carriers have increased breast screening and a risk-reducing salpingo-oophorectomy. They are also given the option to have a risk-reducing mastectomy. The process of deciding if and when to undergo prophylactic surgery has been found to be a complex and difficult process for many carriers. To evaluate the decision-making process, recorded interviews were conducted with 20 <i>BRCA1</i> and <i>BRCA2</i> mutation carriers. Information about the cancer risk management decision-making process was analyzed using grounded theory. Factors involved in decision-making, ease of decision-making, and individuals involved in the decision-making process emerged as major themes. Mutation carriers who have not had breast cancer (previvors) were found to have a more difficult time coming to a cancer risk management decision than women with a breast cancer history. Physicians were often discussed as being an integral part of the decision-making process by providing support and management recommendations. Family members and other mutation carriers filled a similar role during the decision-making process by providing decisional and emotional support for carriers. Genetic counselors were short-term providers of risk information and management recommendations for this study population. If a carrier was not receiving the information or support she needed from one of these groups, she often turned to another party, most commonly a healthcare provider. Thus, data from this study suggests that previvors or mutation carriers struggling with the risk management decision-making process may need additional support and information to assist them during this process. It is important that healthcare providers are educated about risk-management strategies for HBOC and work together to best help mutation carriers through the decision-making process. In summary, this study revealed that women with <i>BRCA1</i> and <i>BRCA2</i> mutations utilize physicians, genetic counselors, family members, and other mutation carriers in the cancer risk management decision-making process. The support and assistance from these individuals can impact the decision-making process. 2016-09-12 English text The Ohio State University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=osu1459588788 http://rave.ohiolink.edu/etdc/view?acc_num=osu1459588788 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
| collection |
NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
Genetics Health Care Health Care Management BRCA1 BRCA2 HBOC management decision-making risk-reduction risk-reducing surgery surgical decision screening decision surveillance decision ease of decision-making physician doctor genetic counselor decision-making factors |
| spellingShingle |
Genetics Health Care Health Care Management BRCA1 BRCA2 HBOC management decision-making risk-reduction risk-reducing surgery surgical decision screening decision surveillance decision ease of decision-making physician doctor genetic counselor decision-making factors Puski, Athena Joy Bowen The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers |
| author |
Puski, Athena Joy Bowen |
| author_facet |
Puski, Athena Joy Bowen |
| author_sort |
Puski, Athena Joy Bowen |
| title |
The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers |
| title_short |
The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers |
| title_full |
The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers |
| title_fullStr |
The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers |
| title_full_unstemmed |
The Surgical and Management Decision-Making Process of <i>BRCA1</i> and <i>BRCA2</i> Mutation Carriers |
| title_sort |
surgical and management decision-making process of <i>brca1</i> and <i>brca2</i> mutation carriers |
| publisher |
The Ohio State University / OhioLINK |
| publishDate |
2016 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=osu1459588788 |
| work_keys_str_mv |
AT puskiathenajoybowen thesurgicalandmanagementdecisionmakingprocessofibrca1iandibrca2imutationcarriers AT puskiathenajoybowen surgicalandmanagementdecisionmakingprocessofibrca1iandibrca2imutationcarriers |
| _version_ |
1719439657215721472 |