A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth
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| Language: | English |
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The Ohio State University / OhioLINK
2015
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| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=osu1437169789 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-osu14371697892021-08-03T06:32:07Z A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth Bultema, Kristy Dentistry liposomal bupivacaine bupivacaine HCl pain control pain tooth teeth numbness anesthesia anesthetic symptomatic irreversible pulpitis symptomatic vital teeth untreated endodontics vital Studies from medical literature have demonstrated prolonged pain relief and reduction in opioid utilization for up to 72 hours postoperatively in patients that received post-surgical infiltration injections with liposomal bupivacaine. At the present time, there are no studies in dental literature that have investigated liposomal bupivacaine for pain control in endodontics. The purpose of this double-blind, randomized controlled trial was to compare bupivacaine HCl to liposomal bupivacaine for endodontic pain control in untreated symptomatic vital posterior teeth in patients experiencing moderate to severe pain. One hundred adult patients were randomly divided into two groups and received either 4 mL of liposomal bupivacaine (13.3 mg/mL) or 4 mL of 0.5% bupivacaine HCl with 1:200,000 epinephrine by infiltration following injection with 1.8 mL of 2% lidocaine with 1:100,000 epinephrine via infiltration or inferior alveolar nerve block. Patients received a diary for the day of the appointment (day 0) and three days post-injection to record tooth numbness, lip numbness, pain levels and analgesics (non-narcotic and narcotic) utilization. No significant differences were found between treatment groups for tooth numbness, pain, use of non-narcotic and narcotic pain medications. A statistically significant difference in lip numbness was found on day 1 to day 3 for the liposomal bupivacaine group. In conclusion, liposomal bupivacaine did not provide prolonged pain control, nor did it reduce analgesic consumption when used for untreated posterior symptomatic vital teeth. 2015-10-14 English text The Ohio State University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=osu1437169789 http://rave.ohiolink.edu/etdc/view?acc_num=osu1437169789 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
Dentistry liposomal bupivacaine bupivacaine HCl pain control pain tooth teeth numbness anesthesia anesthetic symptomatic irreversible pulpitis symptomatic vital teeth untreated endodontics vital |
| spellingShingle |
Dentistry liposomal bupivacaine bupivacaine HCl pain control pain tooth teeth numbness anesthesia anesthetic symptomatic irreversible pulpitis symptomatic vital teeth untreated endodontics vital Bultema, Kristy A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth |
| author |
Bultema, Kristy |
| author_facet |
Bultema, Kristy |
| author_sort |
Bultema, Kristy |
| title |
A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth |
| title_short |
A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth |
| title_full |
A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth |
| title_fullStr |
A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth |
| title_full_unstemmed |
A comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth |
| title_sort |
comparison of liposomal bupivacaine and bupivacaine for pain control in untreated symptomatic vital teeth |
| publisher |
The Ohio State University / OhioLINK |
| publishDate |
2015 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=osu1437169789 |
| work_keys_str_mv |
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| _version_ |
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