A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability
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| Language: | English |
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The Ohio State University / OhioLINK
2014
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| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=osu1397722882 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-osu13977228822021-08-03T06:23:49Z A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability Cole, Mary Elizabeth Physical Anthropology porosity pore haversian canal vascular canal resorption bay trabecularization intraskeletal variability remodeling resorption brightfield microscopy semi-automatic relative cortical area parabolic index Within human populations, differences in bone mass may be attributed to variation in environmental factors such as diet, health, and physical activity. Relative cortical area (RCA) and the parabolic index (PI) both quantify bone mass by calculating the percentage of a cross-section of bone occupied by the solid region of the cortex. Yet the cortex is not solid, being perforated with numerous vascular channels and resorptive spaces. By subtracting these porous voids from cortical area, anthropologists can avoid overestimations of bone mass that distort inferences about physical activity and health. This study presents a semi-automated protocol for quantifying the porosity of a cortex using brightfield microscopy. The protocol automatically differentiates between cortical pores and resorption bays that have coalesced to become “trabecularized” at the endosteal border. This expedited method does not produce significantly different values than those obtained by manually measuring each pore, as tested on a sample of eleven ribs (p = 0.532). Correction for cortical and total porosity significantly reduced values of RCA and PI in femora, tibiae, and ribs of nine individuals. Within single individuals, the rib had significantly greater trabecularized porosity than the femur (p < 0.0009) or tibia (p = 0.004). This trabecularization was localized to the cutaneous cortex of the rib (p = 0.011). Cyclical tension of this cortex during respiration may produce the mechanical loading and microdamage that drives this resorption bay coalescence at the endosteal border. 2014-08-01 English text The Ohio State University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=osu1397722882 http://rave.ohiolink.edu/etdc/view?acc_num=osu1397722882 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
| collection |
NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
Physical Anthropology porosity pore haversian canal vascular canal resorption bay trabecularization intraskeletal variability remodeling resorption brightfield microscopy semi-automatic relative cortical area parabolic index |
| spellingShingle |
Physical Anthropology porosity pore haversian canal vascular canal resorption bay trabecularization intraskeletal variability remodeling resorption brightfield microscopy semi-automatic relative cortical area parabolic index Cole, Mary Elizabeth A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability |
| author |
Cole, Mary Elizabeth |
| author_facet |
Cole, Mary Elizabeth |
| author_sort |
Cole, Mary Elizabeth |
| title |
A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability |
| title_short |
A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability |
| title_full |
A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability |
| title_fullStr |
A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability |
| title_full_unstemmed |
A Semi-Automatic Method for Intracortical Porosity Quantification With Application to Intraskeletal Variability |
| title_sort |
semi-automatic method for intracortical porosity quantification with application to intraskeletal variability |
| publisher |
The Ohio State University / OhioLINK |
| publishDate |
2014 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=osu1397722882 |
| work_keys_str_mv |
AT colemaryelizabeth asemiautomaticmethodforintracorticalporosityquantificationwithapplicationtointraskeletalvariability AT colemaryelizabeth semiautomaticmethodforintracorticalporosityquantificationwithapplicationtointraskeletalvariability |
| _version_ |
1719436024227037184 |