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ndltd-OhioLink-oai-etd.ohiolink.edu-osu1267709402
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oai_dc
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ndltd-OhioLink-oai-etd.ohiolink.edu-osu12677094022021-08-03T05:58:46Z Predictors of Success for Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Retrospective Review Ausich, Mary Kathryn Background/ Objective: Complications can ensue from uncontrolled type 1 diabetes, resulting in compromised quality and duration of life, and increased health care costs. The provision of insulin is achieved by multiple daily injections (MDI) or by insulin pump through continuous subcutaneous insulin infusion (CSII). The primary objective was to determine the difference between hemoglobin A1c (HbA1c) before and after the switch from MDI to CSII therapy. Methods: In this retrospective medical record review, paired t-tests were used for all of the pre-post comparisons. To determine whether external factors were related to a successful reduction in HbA1c after pump initiation, the pre-post HbA1c difference was used as the outcome in a linear regression model, and potential patient characteristic covariates were evaluated univariately for their predictive ability: age, gender, duration of diabetes, age at diagnosis, average insulin pre-pump units (absolute and per kg body weight), weight, insulin and pump types, and the presence of various complications. Of the 107 subjects initially identified, 42 subjects met inclusion criteria. Results: The average HbA1c of participants decreased by 0.55% from pre-pump values (P = 0.0001), the average daily insulin dose per kilogram of body weight decreased by 0.061 U/kg, (P = 0.0029), and weight decreased by 0.07 kg. (P=0.86). None of the continuous or categorical variables were found to be statistically significant at predicting a pre- to post-reduction in HbA1c levels. Conclusions: This study suggests that all study participants, regardless of patient characteristics, benefited from the transition from MDI to CSII therapy. 2010-08-23 English text The Ohio State University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=osu1267709402 http://rave.ohiolink.edu/etdc/view?acc_num=osu1267709402 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
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| collection |
NDLTD
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| language |
English
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| sources |
NDLTD
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| author |
Ausich, Mary Kathryn
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| spellingShingle |
Ausich, Mary Kathryn
Predictors of Success for Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Retrospective Review
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| author_facet |
Ausich, Mary Kathryn
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| author_sort |
Ausich, Mary Kathryn
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| title |
Predictors of Success for Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Retrospective Review
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| title_short |
Predictors of Success for Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Retrospective Review
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| title_full |
Predictors of Success for Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Retrospective Review
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| title_fullStr |
Predictors of Success for Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Retrospective Review
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| title_full_unstemmed |
Predictors of Success for Adults with Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Therapy: A Retrospective Review
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| title_sort |
predictors of success for adults with type 1 diabetes on continuous subcutaneous insulin infusion therapy: a retrospective review
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| publisher |
The Ohio State University / OhioLINK
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| publishDate |
2010
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| url |
http://rave.ohiolink.edu/etdc/view?acc_num=osu1267709402
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| work_keys_str_mv |
AT ausichmarykathryn predictorsofsuccessforadultswithtype1diabetesoncontinuoussubcutaneousinsulininfusiontherapyaretrospectivereview
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| _version_ |
1719428816041934848
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