Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation

Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation

Bibliographic Details
Main Author: Lubelski, Ryan Edward
Language:English
Published: Miami University / OhioLINK 2019
Subjects:
Biochemistry
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=miami1574705098076537
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-miami15747050980765372021-08-03T07:13:25Z Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation Lubelski, Ryan Edward Biochemistry The aesthetic appeal and cosmetic importance of the dentition has driven the need to better understand the mechanisms involved in stain formation. Staining can occur when chromogenic compounds like tannins bind with proteins on the tooth surface and undergo oxidation to form brown-colored complexes. Recent evidence suggests that metal salts and cationic surfactants found in certain oral health care products may also contribute to stain formation. The majority of this thesis is dedicated to understanding what role the presence of metals may have during this tannin-protein complexation process. These investigations were carried out utilizing solution-based precipitation experiments between the condensed tannin procyanidin (PC) and bovine serum albumin (BSA). The results presented here reveal that metals can effect both the quantitative and qualitative nature of tannin-protein complexes, and that these properties depend on both the relative proportions of tannin to metal (T:M) and tannin to protein (T:P). The other objective of this thesis was to determine the effect of the cationic surfactant CPC on the tannin-protein complexation process. The results for these experiments revealed that CPC could precipitate tannin in both the presence and absence of protein or metal, but overall had little effect on the complexation process. 2019-11-25 English text Miami University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=miami1574705098076537 http://rave.ohiolink.edu/etdc/view?acc_num=miami1574705098076537 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Biochemistry
spellingShingle Biochemistry
Lubelski, Ryan Edward
Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation
author Lubelski, Ryan Edward
author_facet Lubelski, Ryan Edward
author_sort Lubelski, Ryan Edward
title Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation
title_short Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation
title_full Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation
title_fullStr Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation
title_full_unstemmed Effect Of Metals And Cetylpyridinium Chloride On Tannin-Protein Interactions: Potential Roles In Extrinsic Teeth Stain Formation
title_sort effect of metals and cetylpyridinium chloride on tannin-protein interactions: potential roles in extrinsic teeth stain formation
publisher Miami University / OhioLINK
publishDate 2019
url http://rave.ohiolink.edu/etdc/view?acc_num=miami1574705098076537
work_keys_str_mv AT lubelskiryanedward effectofmetalsandcetylpyridiniumchlorideontanninproteininteractionspotentialrolesinextrinsicteethstainformation
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