Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels
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Miami University / OhioLINK
2018
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| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-miami1532976274272611 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-miami15329762742726112021-08-03T07:07:53Z Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels Thomas, Caitlyn Alyse Kinesiology Resistin Physical Activity Insulin Sensitivity Age A variety of cytokines, including resistin, adiponectin, endothelin-1 (ET-1) and insulin-like growth factor-1 (IGF-1), are thought to influence adipose and endothelial tissue function. The PURPOSE of this study was to assess the relationships among age, physical activity level, insulin sensitivity and resistin, adiponectin, ET-1 and IGF-1 levels in healthy young and older adults. METHODS: A sample of 20 young (age: 21.0±1.2y) and 20 older (age: 68.4±4.0y) adults was used. The following were assessed: habitual physical activity level (PA); body composition; and fasting serum levels of resistin, adiponectin, ET-1, IGF-1, glucose and insulin. The homeostatic model assessment of insulin resistance (HOMA-IR) was calculated. RESULTS: PA level was not correlated with any protein, glucose or insulin levels. There were no significant differences in resistin and adiponectin levels between young and old subjects (p = 0.056; p = 0.81). There were significant differences in ET-1 and IGF-1 levels between young and old subjects (p= 0.01; p= 2.15 x 10-7). Adiponectin and IGF-1 were inversely correlated with BMI (p = 0.004; p= 0.002). HOMA-IR was positively correlated with BF% (p = 0.015). CONCLUSIONS: Resistin, adiponectin, ET-1, IGF-1 and PA levels do not appear to be predictive of insulin sensitivity in young or older adults. 2018-07-30 English text Miami University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611 http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
Kinesiology Resistin Physical Activity Insulin Sensitivity Age |
| spellingShingle |
Kinesiology Resistin Physical Activity Insulin Sensitivity Age Thomas, Caitlyn Alyse Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels |
| author |
Thomas, Caitlyn Alyse |
| author_facet |
Thomas, Caitlyn Alyse |
| author_sort |
Thomas, Caitlyn Alyse |
| title |
Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels |
| title_short |
Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels |
| title_full |
Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels |
| title_fullStr |
Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels |
| title_full_unstemmed |
Associations Among Age, Physical Activity, Insulin Sensitivity, Resistin, Endothelin-1, Adiponectin, and IGF-1 Levels |
| title_sort |
associations among age, physical activity, insulin sensitivity, resistin, endothelin-1, adiponectin, and igf-1 levels |
| publisher |
Miami University / OhioLINK |
| publishDate |
2018 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=miami1532976274272611 |
| work_keys_str_mv |
AT thomascaitlynalyse associationsamongagephysicalactivityinsulinsensitivityresistinendothelin1adiponectinandigf1levels |
| _version_ |
1719454397506781184 |