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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-dayton15118037463315932021-08-03T07:04:45Z Nanostructured Microcantilever for the Detection of Volatile Compounds McNeilly, Ryan J. Biochemistry Biomedical Engineering Chemical Engineering Electrical Engineering Mechanical Engineering biosensor sensor microcantilever volatile organic compound nanostructure glancing angle deposition In this study, nanostructured, functionalized microcantilevers have been designed, fabricated, and characterized for the sensing of volatile organic compounds. Sensing devices were fabricated with either four or eight hammerhead-shaped cantilevers. These cantilevers vibrate laterally in-plane making them highly suitable for sensing in both air and liquid. Silicon oxide nanostructure was deposited on the cantilevers to increase the surface area and sensitivity of the devices. Molecular recognition peptides were chemically tethered to the surfaces to create a selective response for the analytes of interest. When the analytes have bound to the surface of the cantilever, a shift in resonance frequency is produced and detected by piezoresistive sensors. This frequency shift can be used to determine the mass of analyte bound to the surface. The cantilever sensors are expected to provide fast and highly sensitive detection, and can be fabricated in an array format for sensing multiple compounds in complex samples. The nanostructured cantilever sensors show strong potential for applications in medical, environmental, food safety, and hazardous gas monitoring applications. 2017-12-20 English text University of Dayton / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=dayton1511803746331593 http://rave.ohiolink.edu/etdc/view?acc_num=dayton1511803746331593 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Biochemistry
Biomedical Engineering
Chemical Engineering
Electrical Engineering
Mechanical Engineering
biosensor
sensor
microcantilever
volatile organic compound
nanostructure
glancing angle deposition
spellingShingle Biochemistry
Biomedical Engineering
Chemical Engineering
Electrical Engineering
Mechanical Engineering
biosensor
sensor
microcantilever
volatile organic compound
nanostructure
glancing angle deposition
McNeilly, Ryan J.
Nanostructured Microcantilever for the Detection of Volatile Compounds
author McNeilly, Ryan J.
author_facet McNeilly, Ryan J.
author_sort McNeilly, Ryan J.
title Nanostructured Microcantilever for the Detection of Volatile Compounds
title_short Nanostructured Microcantilever for the Detection of Volatile Compounds
title_full Nanostructured Microcantilever for the Detection of Volatile Compounds
title_fullStr Nanostructured Microcantilever for the Detection of Volatile Compounds
title_full_unstemmed Nanostructured Microcantilever for the Detection of Volatile Compounds
title_sort nanostructured microcantilever for the detection of volatile compounds
publisher University of Dayton / OhioLINK
publishDate 2017
url http://rave.ohiolink.edu/etdc/view?acc_num=dayton1511803746331593
work_keys_str_mv AT mcneillyryanj nanostructuredmicrocantileverforthedetectionofvolatilecompounds
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