A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT

Bibliographic Details
Main Author:	Dehghanzadeh, Parisa
Language:	English
Published:	Case Western Reserve University School of Graduate Studies / OhioLINK 2021
Subjects:	Electrical Engineering Biomedical Engineering
Online Access:	http://rave.ohiolink.edu/etdc/view?acc_num=case1619048915597347

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spelling	ndltd-OhioLink-oai-etd.ohiolink.edu-case16190489155973472021-12-02T05:18:12Z A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT Dehghanzadeh, Parisa Electrical Engineering Biomedical Engineering This PhD thesis develops a microsystem, including an external unit and an implantableultrasonic measurement device, dedicated to bladder volume (BV) estimation, which isclinically important for patients suffering from lower urinary tract dysfunction. The developedmicrosystem integrates wireless power and data transfer, ultrasonic measurementswith a piezoelectric transducer (PZT), and BV estimation from received ultrasoundsignals. As the first step, ultrasonic BV measurement methods are investigatedand A-mode ultrasound, i.e., using signals detected by a single transducer, is verified forhigh efficiency BV measurement. Moreover, a proof-of-concept wearable device usingA-mode ultrasound scans is developed which can estimate the volume of a sphericalbladder phantom with high fidelity (within 15% error).Next, a self-optimizing near-field power/data inductive link paradigm is proposedfor use in biomedical implants. Specifically, the fundamental trade-offs between powerand data transfer efficiencies that occur during simultaneous power and data transferthrough near-field inductive links is studied. A mathematical analysis is used to establishthe relationship between power transfer efficiency (PTE) and channel capacity as a function of link parameters such as coupling coefficient (k), load resistance, and surroundingenvironment. In addition, real-time adaptation of the link parameters is proposedto automatically optimize the power-data trade-off over a wide range of distancesand coupling coefficients. A bench-top prototype of such an adaptive link is demonstratedat a center frequency of 13.56 MHz. The prototype uses an ultrasound transducerto measure d with accuracy C 0.1 mm, and uses this information to autonomously optimizeboth data rate (up to ~50 Mbps) and PTE (up to ~25%) as the coil-coil distancevaries within the 4-15mm range.Finally, a BV measurement microsystemincluding an external unit and an implantabledevice is developed. The external unit sends power and command data to the implantabledevice and receives measurement data from it through an inductive link, while the implantabledevice applies A-mode ultrasound measurement to estimate BV. The systemand circuit design details and simulation results for the microsystem are presented. Furthermore,the results of using the proposed microsystem for in-vitro BV measurementsare provided, thus verifying its functionality for real-time BV monitoring. 2021-06-21 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1619048915597347 http://rave.ohiolink.edu/etdc/view?acc_num=case1619048915597347 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection	NDLTD
language	English
sources	NDLTD
topic	Electrical Engineering Biomedical Engineering
spellingShingle	Electrical Engineering Biomedical Engineering Dehghanzadeh, Parisa A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT
author	Dehghanzadeh, Parisa
author_facet	Dehghanzadeh, Parisa
author_sort	Dehghanzadeh, Parisa
title	A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT
title_short	A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT
title_full	A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT
title_fullStr	A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT
title_full_unstemmed	A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT
title_sort	miniaturized wireless ultrasound system for implantable bladder volume measurement
publisher	Case Western Reserve University School of Graduate Studies / OhioLINK
publishDate	2021
url	http://rave.ohiolink.edu/etdc/view?acc_num=case1619048915597347
work_keys_str_mv	AT dehghanzadehparisa aminiaturizedwirelessultrasoundsystemforimplantablebladdervolumemeasurement AT dehghanzadehparisa miniaturizedwirelessultrasoundsystemforimplantablebladdervolumemeasurement
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A MINIATURIZED WIRELESS ULTRASOUND SYSTEM FOR IMPLANTABLE BLADDER VOLUME MEASUREMENT

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