A Mechanistic Framework for Telomerase Kinetics Identifies New Opportunities for Therapeutic Interventions

A Mechanistic Framework for Telomerase Kinetics Identifies New Opportunities for Therapeutic Interventions

Bibliographic Details
Main Author:	Hernandez-Sanchez, Wilnelly
Language:	English
Published:	Case Western Reserve University School of Graduate Studies / OhioLINK 2020
Subjects:	Pharmacology Biochemistry Oncology
Online Access:	http://rave.ohiolink.edu/etdc/view?acc_num=case1586191570745256

Similar Items

Investigating the Mechanistic Basis for Epigenetic Modifications Induced by Tungsten
by: Laulicht, Freda
Published: (2016)

Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology
by: Kirill Peskov, et al.
Published: (2019-04-01)

Antineoplastic activity of a novel ruthenium complex against human hepatocellular carcinoma (HepG2) and human cervical adenocarcinoma (HeLa) cells
by: Carlos Eduardo Alves de Souza, et al.
Published: (2020-05-01)

Novel Biological Insights and Therapeutic Approaches in High-Risk Acute Myeloid Leukemia
by: Alachkar, Houda
Published: (2012)

Prolyl Isomerase Pin1 Is a Conditional Tumor Suppressor
by: Teng, Brian Lew
Published: (2011)

Pharmacological Stimulation of Nicotinamide Phosphoribosyltransferase with P7c3-A20 as a Protective Strategy for Paclitaxel-Induced Peripheral Neuropathy
by: LoCoco, Peter M.
Published: (2017)

Preclinical Development of New Alkylating Oligopeptides for Cancer Therapy
by: Gullbo, Joachim
Published: (2003)

Structure-based Design of Small Molecule Inhibitors of HIV-1 Entry
by: Le-Khac, Matthew
Published: (2013)

Response to pegylated interferon in a COVID‐19 positive male with metastatic jejunal neuroendocrine tumor treated with everolimus
by: Arthur E. Frankel, et al.
Published: (2021-06-01)

Extracellular Inflammatory Signaling from Dysfunctional Telomeres
by: Wang, Zhuo
Published: (2018)

Osteoimmuno-Oncology: Therapeutic Opportunities for Targeting Immune Cells in Bone Metastasis
by: Tiina E. Kähkönen, et al.
Published: (2021-06-01)

Inhibition of D-Amino acid oxidase by phenothiazines
by: Harris, Sheldon R.
Published: (2019)

Aberrations in Nicotinic Acetylcholine Receptor Structure, Function, and Expression: Implications in Disease
by: Frank Salamone, et al.
Published: (2020-12-01)

A fret investigation into molecular mechanisms of cardiac troponin activation in reconstituted thin filaments
by: Moutsoglou, Maria Eleni
Published: (2016)

Investigations into the potential for 3,4-methylenedioxymethamphetamine to induce neurotoxic terminal damage to serotonergic neurons
by: Biezonski, Dominik
Published: (2009)

Understanding the Mechanistic Regulation of Rubisco activase Using Steady State Enzyme Kinetic Analysis of ATPase Activity
Published: (2015)

Defining the Mechanism of Methuosis, a Non-apoptotic Cell Death Pathway, Induced by Indolyl Chalcone Compounds in Glioblastoma Cells
by: Mbah, Nneka Elizabeth
Published: (2016)

The Requirement for Oxygen in the Maturation and Secretion of Soluble urokinase Plasminogen Activator Receptor (uPAR)
by: Rumantir, Ryan Allister
Published: (2013)

The Requirement for Oxygen in the Maturation and Secretion of Soluble urokinase Plasminogen Activator Receptor (uPAR)
by: Rumantir, Ryan Allister
Published: (2013)

Cellular Pharmacology of the Novel Antitumoural Cyanoguanidine CHS 828
by: Lövborg, Henrik
Published: (2004)

Characterization of Intrinsic and Extrinsic Factors that Regulate Human Telomerase Repeat Addition
Published: (2018)

FindSim: A Framework for Integrating Neuronal Data and Signaling Models
by: Nisha A. Viswan, et al.
Published: (2018-06-01)

Therapeutic role of taurine as antioxidant in reducing hypertension risks in rats
by: Marwan A. Ibrahim, et al.
Published: (2020-01-01)

Structural Characterization of an Engineered Adenovirus Vector and Complement-mediated Inactivation of Adenovirus
by: Emerson, Corey
Published: (2021)

Glutathione Reductase, Redox Homeostasis, and Mitochondrial Dysfunction
by: REN, PEI
Published: (2013)

Novel signaling mechanisms for Transforming Growth Factor-beta; activated kinase-1 (TAK1) in microtubule and endoplasmic reticulum dynamics
by: Shah, Nirav, Shah
Published: (2018)

Cardio-Oncology: Success Breeds New Challenges, Opportunities
by: Charles A. Bomzer, et al.
Published: (2014-08-01)

Tyrosine Kinase Inhibitors in Cancer: Breakthrough and Challenges of Targeted Therapy
by: Charles Pottier, et al.
Published: (2020-03-01)

Clinical Pharmacology of Antibody-Drug Conjugates
by: Iftekhar Mahmood
Published: (2021-05-01)

Alternatives to Animal Testing : Proceedings of Asian Congress 2016
Published: (2019)

Alternatives to Animal Testing Proceedings of Asian Congress 2016
Published: (2019)

Chapter Telomere Maintenance in Organisms without Telomerase
by: Mason, James M.
Published: (2011)

Chapter Telomere Maintenance in Organisms without Telomerase
Published: (2011)

Mechanisms and therapeutic targeting of NT5C2 mutations in relapsed acute lymphoblastic leukemia
by: Dieck, Chelsea
Published: (2019)

Cancer Genetics and Therapeutic Opportunities in Urologic Practice
by: Jacob J. Adashek, et al.
Published: (2020-03-01)

Evolution of Telomerase RNA
Published: (2019)

Novel Therapeutic Concepts in Targeting Glioma
Published: (2012)

EVALUATION OF A SMALL MOLECULE AGONIST OF EPHA2 RECEPTOR TYROSINE KINASE AND COPALIC ACID ANALOGS AS PROSTATE CANCER THERAPEUTICS
by: Idippily, Nethrie
Published: (2018)

Pharmacology and Therapeutics
Published: (2014)

Mechanistic insights into a reverse polymerase
by: Smith, Brian A.
Published: (2012)

Cannot write session to /tmp/vufind_sessions/sess_nmr0pfj80bags3jq6sak7f1ov8