Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants

Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants

Bibliographic Details
Main Author: Pax, Benjamin M.
Language:English
Published: Case Western Reserve University School of Graduate Studies / OhioLINK 2018
Subjects:
Electrical Engineering
Computer Science
Statistics
Epidemiology
Mathematics
Medicine
Bronchopulmonary Dysplasia
VLBWI
ELGANs
Multinomial Logistic Regression
Ordinal Logistic Regression
a Priori
Longitudinal
Risk Factors
Prediction
Statistical Model
BPD
ROP
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=case1522686042230784
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-case15226860422307842021-08-03T07:05:31Z Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants Pax, Benjamin M. Electrical Engineering Computer Science Statistics Epidemiology Mathematics Medicine Bronchopulmonary Dysplasia VLBWI ELGANs Multinomial Logistic Regression Ordinal Logistic Regression a Priori Longitudinal Risk Factors Prediction Statistical Model BPD ROP Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature InfantsABSTRACTByBENJAMIN PAXThis thesis seeks to identify at risk premature infants for Bronchopulmonary Dysplasia (BPD) and to identify new longitudinal risk factors for BPD by postnatal day. A calculator tool has been created to estimate risk of BPD based on a priori risk factors as well as additional clinical variables. The estimator seeks to estimate outcome based on BPD severity (no BPD, mild, moderate, and severe) as defined by the NIH. The variables examined were as follows: birth weight (BW), gestational age (GA), race and ethnicity, sex, type of respiratory support (no support, nasal cannula/hood, CPAP, ventilator, oscillator), mean airway pressure, supplementary oxygen, oxygen severity index, intermittent hypoxemic events, FiO2, SpO2, Snap score, sepsis, and multiple births. Models were evaluated by using a C statistic on a series of multinomial logistic regression models on postnatal days with C Statistic 0.789 on day 1 to 0.945 on day 56. 2018-06-01 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1522686042230784 http://rave.ohiolink.edu/etdc/view?acc_num=case1522686042230784 unrestricted This thesis or dissertation is protected by copyright: some rights reserved. It is licensed for use under a Creative Commons license. Specific terms and permissions are available from this document's record in the OhioLINK ETD Center.
collection NDLTD
language English
sources NDLTD
topic Electrical Engineering
Computer Science
Statistics
Epidemiology
Mathematics
Medicine
Bronchopulmonary Dysplasia
VLBWI
ELGANs
Multinomial Logistic Regression
Ordinal Logistic Regression
a Priori
Longitudinal
Risk Factors
Prediction
Statistical Model
BPD
ROP
spellingShingle Electrical Engineering
Computer Science
Statistics
Epidemiology
Mathematics
Medicine
Bronchopulmonary Dysplasia
VLBWI
ELGANs
Multinomial Logistic Regression
Ordinal Logistic Regression
a Priori
Longitudinal
Risk Factors
Prediction
Statistical Model
BPD
ROP
Pax, Benjamin M.
Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants
author Pax, Benjamin M.
author_facet Pax, Benjamin M.
author_sort Pax, Benjamin M.
title Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants
title_short Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants
title_full Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants
title_fullStr Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants
title_full_unstemmed Prediction of Bronchopulmonary Dysplasia by a Priori and Longitudinal Risk Factors in Extremely Premature Infants
title_sort prediction of bronchopulmonary dysplasia by a priori and longitudinal risk factors in extremely premature infants
publisher Case Western Reserve University School of Graduate Studies / OhioLINK
publishDate 2018
url http://rave.ohiolink.edu/etdc/view?acc_num=case1522686042230784
work_keys_str_mv AT paxbenjaminm predictionofbronchopulmonarydysplasiabyaprioriandlongitudinalriskfactorsinextremelyprematureinfants
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