Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins

Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins

Bibliographic Details
Main Author: Tustan, Alisar Nicole
Language:English
Published: Case Western Reserve University School of Graduate Studies / OhioLINK 2018
Subjects:
Biochemistry
Pharmaceuticals
insulin
diabetes
hepatoselective
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=case1511262462584764
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-case15112624625847642021-08-03T07:04:34Z Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins Tustan, Alisar Nicole Biochemistry Pharmaceuticals insulin diabetes hepatoselective Recent evidence in the field of insulin research has suggested that insulin signaling occurs in a manner that is tissue specific. Less evidence exists to show that this tissue specificity (which entails suppression of glucose production and stimulation of fat synthesis in liver, stimulation of fat synthesis in adipose tissue, and stimulation of glucose uptake) can be directed depending on the insulin variant. The collected data from studies detailed below could both illustrate this concept and offer hope for future discoveries of insulin variants that are optimally effective in the cells that are most important for people suffering from diabetes: hepatocytes and adipocytes. 2018-02-01 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1511262462584764 http://rave.ohiolink.edu/etdc/view?acc_num=case1511262462584764 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Biochemistry
Pharmaceuticals
insulin
diabetes
hepatoselective
spellingShingle Biochemistry
Pharmaceuticals
insulin
diabetes
hepatoselective
Tustan, Alisar Nicole
Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins
author Tustan, Alisar Nicole
author_facet Tustan, Alisar Nicole
author_sort Tustan, Alisar Nicole
title Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins
title_short Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins
title_full Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins
title_fullStr Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins
title_full_unstemmed Comparative Effects of Insulins: a Prospective Case for Tissue Specific Insulins
title_sort comparative effects of insulins: a prospective case for tissue specific insulins
publisher Case Western Reserve University School of Graduate Studies / OhioLINK
publishDate 2018
url http://rave.ohiolink.edu/etdc/view?acc_num=case1511262462584764
work_keys_str_mv AT tustanalisarnicole comparativeeffectsofinsulinsaprospectivecasefortissuespecificinsulins
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