DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING
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Case Western Reserve University School of Graduate Studies / OhioLINK
2017
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Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=case1480691677961147 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-case14806916779611472021-08-03T06:39:22Z DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING Jiang, Yun Biomedical Engineering Magnetic Resonance Imaging Magnetic Resonance Fingerprinting T1 T2 relaxation MRI MRF Quantification of tissue properties has long been a research goal in Magnetic Resonance Imaging (MRI). However, the long acquisition time of the conventional quantitative method prohibited its adoption in the clinic. The recently proposed Magnetic Resonance Fingerprinting (MRF) is a novel framework that simultaneously quantifies multiple tissue properties using pseudorandom acquisition parameters. It breaks the convention of MRI which acquires a steady- state signal with fixed acquisition parameters, and thus MRF can exploit all degrees of freedom in the pulse sequence design. With nearly unlimited choices of sequence parameters, the thesis explored and presented MRF methods based on the QUick Echo Split NMR technique (QUEST) to reduce the Specific Absorption Rate (SAR), the Fast Imaging with Steady-state Precession (FISP) to improve the performance with off-resonance, the Double Echo Steady-state (DESS) to quantify diffusion, and a Simultaneous MultiSlice (SMS) MRF to further reduce the acquisition time. The development of these novel methods improves the robustness of MRF and have the potential to extend MRF to wide ranges of applications. 2017-02-08 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1480691677961147 http://rave.ohiolink.edu/etdc/view?acc_num=case1480691677961147 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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NDLTD |
language |
English |
sources |
NDLTD |
topic |
Biomedical Engineering Magnetic Resonance Imaging Magnetic Resonance Fingerprinting T1 T2 relaxation MRI MRF |
spellingShingle |
Biomedical Engineering Magnetic Resonance Imaging Magnetic Resonance Fingerprinting T1 T2 relaxation MRI MRF Jiang, Yun DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING |
author |
Jiang, Yun |
author_facet |
Jiang, Yun |
author_sort |
Jiang, Yun |
title |
DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING |
title_short |
DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING |
title_full |
DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING |
title_fullStr |
DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING |
title_full_unstemmed |
DEVELOPMENT OF NOVEL PULSE SEQUENCES FOR MAGNETIC RESONANCE FINGERPRINTING |
title_sort |
development of novel pulse sequences for magnetic resonance fingerprinting |
publisher |
Case Western Reserve University School of Graduate Studies / OhioLINK |
publishDate |
2017 |
url |
http://rave.ohiolink.edu/etdc/view?acc_num=case1480691677961147 |
work_keys_str_mv |
AT jiangyun developmentofnovelpulsesequencesformagneticresonancefingerprinting |
_version_ |
1719440881828757504 |