Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia
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Case Western Reserve University School of Graduate Studies / OhioLINK
2013
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| Online Access: | http://rave.ohiolink.edu/etdc/view?acc_num=case1370591910 |
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ndltd-OhioLink-oai-etd.ohiolink.edu-case13705919102021-08-03T05:24:02Z Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia Hadley, Aaron John Biomedical Engineering Rehabilitation Larynx swallowing functional electrical stimulation pattern detection palatometry hypoglossal nerve laryngeal elevation vocal folds transtracheal stimulation Control of the laryngo-tracheal opening is necessary to balance the body’s constant need of oxygen, phonate speech, and enable safe intake of food. A common result of traumatic brain injury and stroke is paralysis and paresis of the vocal folds, causing impaired breathing, hoarseness, and aspiration. Vocal fold adduction and laryngeal elevation serve as protective mechanisms to divert fluids and food away from the airway and into the esophagus during deglutition. The aims of the current study were to: 1) Examine selective hypoglossal nerve stimulation for laryngeal elevation, 2) Optimize the stimulation angles and parameters of transtracheal stimulation, and 3) Develop an automatic detection algorithm using natural signals from swallowing.Hypoglossal nerve stimulation induced laryngeal elevation to a magnitude approximately equal to that of a natural swallow, and FINE electrodes were shown to be able to selectively activate the muscles of elevation. Transtracheal stimulation, when applied at the optimized angles, was able to induce complete vocal fold adduction. A time-delay artificial neural network was trained to sensitively and selectively detect swallowing using oral pressure signals. This research advances the creation of a closed-loop laryngeal stimulator for dysphagia protection by assessing novel stimulation paradigms, producing an automatic control signal, and combining laryngeal stimulation measures for more complete protection. The results of this research strongly support advancing these techniques to pilot clinical trials. 2013-08-23 English text Case Western Reserve University School of Graduate Studies / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=case1370591910 http://rave.ohiolink.edu/etdc/view?acc_num=case1370591910 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws. |
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NDLTD |
| language |
English |
| sources |
NDLTD |
| topic |
Biomedical Engineering Rehabilitation Larynx swallowing functional electrical stimulation pattern detection palatometry hypoglossal nerve laryngeal elevation vocal folds transtracheal stimulation |
| spellingShingle |
Biomedical Engineering Rehabilitation Larynx swallowing functional electrical stimulation pattern detection palatometry hypoglossal nerve laryngeal elevation vocal folds transtracheal stimulation Hadley, Aaron John Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia |
| author |
Hadley, Aaron John |
| author_facet |
Hadley, Aaron John |
| author_sort |
Hadley, Aaron John |
| title |
Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia |
| title_short |
Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia |
| title_full |
Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia |
| title_fullStr |
Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia |
| title_full_unstemmed |
Dynamic Laryngo-Tracheal Control for Airway Management in Dysphagia |
| title_sort |
dynamic laryngo-tracheal control for airway management in dysphagia |
| publisher |
Case Western Reserve University School of Graduate Studies / OhioLINK |
| publishDate |
2013 |
| url |
http://rave.ohiolink.edu/etdc/view?acc_num=case1370591910 |
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AT hadleyaaronjohn dynamiclaryngotrachealcontrolforairwaymanagementindysphagia |
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