The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate

Bibliographic Details
Main Author: Barkley, Russell A.
Language:English
Published: Bowling Green State University / OhioLINK 1977
Subjects:
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566463048507597
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-bgsu15664630485075972021-08-03T07:12:44Z The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate Barkley, Russell A. Psychology This study attempted to ascertain the effects of methylphenidate on the activity level and attention of hyperkinetic children. It also focused on the determination of which variables predicted the degree to which these children improved during drug treatment. A total of 36 boys ranging in age from 5 to 12 years and having IQs greater than 80 were used in this study. Of these, 18 were referred to local pediatricians, diagnosed as hyperkinetic, and placed on methylphenidate. A second group of 18 boys was obtained from the local community as a control group and matched in age and IQ with the hyperkinetic children. All children were observed on three occasions with each being 7 to 14 days apart. The hyperkinetic children participated in a double-blind drug and placebo crossover design during these three days. On the first day, they were evaluated while off all medication. On the second and third days, they received the drug and placebo in a randomized order such that half received the drug first while the other half received the placebo first. The hyperkinetic children received 10 milligrams of methylphenidate orally within 3 hours prior to evaluation, or they received a placebo. The control boys did not receive any drugs. On each of the 3 days, all boys were evaluated using a variety of measures of activity and attention taken across several structured and free play settings, Parental ratings of activity and tests of math and reading ability were also obtained. The results indicated that methylphenidate improved a variety of types of activity level in the hyperkinetic children across all of the settings. Attention span and concentration to tasks were also improved. Pretreatment levels of concentration to tasks were the best predictors of global drug improvement. This study also found that hyperkinetic children were more active, had shorter attention spans, were less able to concentrate on tasks, were less able to inhibit locomotor activity, and were viewed by their parents as more active than normal children. Despite the positive drug effects, clinical observations suggested that the drug reduced responsiveness to the environment in many of the hyperkinetic children. 1977 English text Bowling Green State University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566463048507597 http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566463048507597 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Psychology
spellingShingle Psychology
Barkley, Russell A.
The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate
author Barkley, Russell A.
author_facet Barkley, Russell A.
author_sort Barkley, Russell A.
title The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate
title_short The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate
title_full The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate
title_fullStr The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate
title_full_unstemmed The Prediction of Differential Responsiveness of Hyperkinetic Children To Methylphenidate
title_sort prediction of differential responsiveness of hyperkinetic children to methylphenidate
publisher Bowling Green State University / OhioLINK
publishDate 1977
url http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1566463048507597
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