DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS

DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS

Bibliographic Details
Main Author: Arutyunyan, Sergey L.
Language:English
Published: Bowling Green State University / OhioLINK 2005
Subjects:
acne
peroxyesters
synthesis
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1126651865
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-bgsu11266518652021-08-03T05:27:44Z DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS Arutyunyan, Sergey L. acne peroxyesters synthesis Acne vulgaris is the most common skin disorder whose pathogenesis appears to be multifactorial. A synthetic scheme for a new multifunctional peroxyester compound for acne treatment was proposed and successfully completed. This compound (8) contains three parts which are expected to serve different functions. A tert-Bu perester moiety would serve as radical generating part for acne treatment. The benzophenone chromophore would photochemically control radical generation. Finally, the diethyleneglycol methyl ether part is expected to increase the skin affinity of the proposed molecule. Compound (8) shows characteristic absorption of the benzophenone chromophore with maxima at 348 and 256 nm. Combinatorial experiments were performed by reacting eight different alcohols with methyl 4-(4-bromomethylbenzoyl) benzoate (4) as the common substrate. 2005-09-15 English text Bowling Green State University / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1126651865 http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1126651865 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic acne
peroxyesters
synthesis
spellingShingle acne
peroxyesters
synthesis
Arutyunyan, Sergey L.
DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS
author Arutyunyan, Sergey L.
author_facet Arutyunyan, Sergey L.
author_sort Arutyunyan, Sergey L.
title DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS
title_short DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS
title_full DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS
title_fullStr DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS
title_full_unstemmed DESIGN OF MULTIFUNCTIONAL MOLECULE FOR TREATMENT OF ACNE SYNTHESIS OF SKIN SOLUBLE BENZOPHENONE PEROXYESTERS
title_sort design of multifunctional molecule for treatment of acne synthesis of skin soluble benzophenone peroxyesters
publisher Bowling Green State University / OhioLINK
publishDate 2005
url http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1126651865
work_keys_str_mv AT arutyunyansergeyl designofmultifunctionalmoleculefortreatmentofacnesynthesisofskinsolublebenzophenoneperoxyesters
_version_ 1719420398991310848

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