Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform

Bibliographic Details
Main Author: Thozhal, Rijo
Language:English
Published: University of Akron / OhioLINK 2015
Subjects:
ECG
HRV
Online Access:http://rave.ohiolink.edu/etdc/view?acc_num=akron1434608401
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spelling ndltd-OhioLink-oai-etd.ohiolink.edu-akron14346084012021-08-03T06:31:40Z Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform Thozhal, Rijo Biomedical Engineering Biomedical Research Electrocardiogram ECG ECG analysis discrete Hermite transform DHmT ischemia pre-diagnostic tool modified limb lead III MLIII MATLAB signal processing beat analysis HRV episode analysis PhysioNet An important driving force in the human circulatory system is the heart. The electrical activity of the heart can be recorded as P, Q, R, S and T waves that constitute an electrocardiogram (ECG) signal. The main method used in this thesis involves the discrete Hermite Transform (DHmT) that provides shape analysis for ECG signals. Earlier work proved that the DHmT method of characterizing ischemia from ECGs was fast and accurate for the ECG signals from precordial lead V4. Myocardial ischemia is a lack of oxygen flow to heart tissue exhibited in ECGs through different shapes. This thesis extends that analysis to limb lead MLIII to characterize ischemia. When used with other leads, analysis of MLIII confirms ischemic characteristics for particular arteries. This work is important because cardiologists tend to characterize such events using different standard ECG leads. The ECG signal shapes can be characterized by a new digital signal transform that is shape-based: the discrete Hermite transform (DHmT), method discovered by Mugler et al. (2000). An online archived database (http://physionet.org) is used for obtaining ECG waveforms from the European ST-T databank. These signals are computationally analyzed using MATLAB programming. The DHmT and related methods are applied to quickly and accurately identify characteristics of ischemia in ST segments. Heartbeats that show artifacts or abnormalities are not included in the analysis. The speed of the computation is such that a 2-hour ECG recording can be processed in 2.19 minutes on a standard PC. It tailors the analysis to the individual patient. The analysis concentrates on MLIII to determine the ischemic characteristic shapes of ST depression and elevation. The results show that high sensitivity, specificity, and positive predictive value are given by this method when applied to ischemic episodes. It is believed that this research into MLIII is the first of its kind. 2015-07-01 English text University of Akron / OhioLINK http://rave.ohiolink.edu/etdc/view?acc_num=akron1434608401 http://rave.ohiolink.edu/etdc/view?acc_num=akron1434608401 unrestricted This thesis or dissertation is protected by copyright: all rights reserved. It may not be copied or redistributed beyond the terms of applicable copyright laws.
collection NDLTD
language English
sources NDLTD
topic Biomedical Engineering
Biomedical Research
Electrocardiogram
ECG
ECG analysis
discrete Hermite transform
DHmT
ischemia
pre-diagnostic tool
modified limb lead III
MLIII
MATLAB
signal processing
beat analysis
HRV
episode analysis
PhysioNet
spellingShingle Biomedical Engineering
Biomedical Research
Electrocardiogram
ECG
ECG analysis
discrete Hermite transform
DHmT
ischemia
pre-diagnostic tool
modified limb lead III
MLIII
MATLAB
signal processing
beat analysis
HRV
episode analysis
PhysioNet
Thozhal, Rijo
Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform
author Thozhal, Rijo
author_facet Thozhal, Rijo
author_sort Thozhal, Rijo
title Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform
title_short Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform
title_full Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform
title_fullStr Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform
title_full_unstemmed Automated ECG Analysis for Characteristics of Ischemia from Limb Lead MLIII Using the Discrete Hermite Transform
title_sort automated ecg analysis for characteristics of ischemia from limb lead mliii using the discrete hermite transform
publisher University of Akron / OhioLINK
publishDate 2015
url http://rave.ohiolink.edu/etdc/view?acc_num=akron1434608401
work_keys_str_mv AT thozhalrijo automatedecganalysisforcharacteristicsofischemiafromlimbleadmliiiusingthediscretehermitetransform
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