Investigations into the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immune suppression: effects on dendritic cell phenotype and function

Investigations into the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immune suppression: effects on dendritic cell phenotype and function

T cell-dependent immune responses are highly sensitive to suppression by exposure to the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), yet direct effects of TCDD on T cells have been difficult to demonstrate. Because the activation of naive T cells is initiated by dendritic c...

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Bibliographic Details
Main Author: Vorderstrasse, Beth A.
Other Authors: Kerkevliet, Nancy I.
Language:en_US
Published: 2012
Subjects:
Dendritic cells
Tetrachlorodibenzodioxin
Immunotoxicology
Online Access:http://hdl.handle.net/1957/32668

Internet

http://hdl.handle.net/1957/32668

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