Elevated ceramide levels contribute to the age-associated decline in vascular endothelial nitric oxide : pharmacologic administration of lipoic acid partially restores function
The vascular endothelium is a single cell layer that lines the lumen of the entire vasculature. It is the site of synthesis of nitric oxide (NO), a vasodilatory compound synthesized by endothelial nitric oxide synthase (eNOS). NO causes intracellular calcium sequestration of the vascular smooth musc...
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| Language: | en_US |
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2012
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| Online Access: | http://hdl.handle.net/1957/31856 |