Determining DNA damage and repair in human cells exposed to metabolites characteristic for tyrosinemia / Etresia van Dyk
Hereditary Tyrosinemia (HTI) is an autosomal recessive disorder caused by a deficiency of fumarylacetoacetate hydrolase (FAH) but the mechanism by which the hepatic and renal symptoms of HTI arise is largely unknown. The current hypothesis is that the final metabolites of tyrosine catabolism (maleyl...
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North-West University
2009
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| Online Access: | http://hdl.handle.net/10394/868 |