Structure and catalytic properties of NRas and its oncogenic mutants
Ras GTPases are signaling proteins that exist in three isoforms, N-Ras, K-Ras and H-Ras that are involved in a variety of signal transduction pathways, including cellular proliferation and survival. Ras acts as a molecular switch, where it is inactive when bound to GDP and propagates its signal when...
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| Online Access: | http://hdl.handle.net/2047/D20321697 |