Exposing the effects of amyloidogenic variants on the maturation of HDL by the conformational analysis of apolipoprotein A-I

Apolipoprotein A-I (apoA-I) is a key protein involved in the production of high-density lipoprotein (HDL) particles. Not only does apoA-I act as a structural scaffold for HDL, making up 70% of the protein composition, it acts as a mediator of protein-protein interactions, a receptor ligand, and an e...

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Online Access:http://hdl.handle.net/2047/D20291521