Development and optimization of electrochemical sensors to detect bacterial pathogens for point-of-care applications

This dissertation focuses on the development and optimization of electrochemical sensors to detect bacterial pathogens for point-of-care applications. Recent spikes in hospital-acquired infections have resurfaced fears of antibiotic-resistant bacteria and their adverse effects on human health. Prese...

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Online Access:http://hdl.handle.net/2047/D20251493
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Summary:This dissertation focuses on the development and optimization of electrochemical sensors to detect bacterial pathogens for point-of-care applications. Recent spikes in hospital-acquired infections have resurfaced fears of antibiotic-resistant bacteria and their adverse effects on human health. Presenting new challenges in pathogenesis and resistance, infections caused by these microorganisms are becoming increasingly difficult to treat, with prompt administration of targeted therapies providing the best chances for patient recovery. To address this emerging threat, this dissertation aims to develop and improve biosensors that will allow for early and rapid detection of these bacterial pathogens.