Brush polymers for nucleic acid delivery and self assembly
Difficult biopharmaceutical characteristics of oligonucleotides, such as poor enzymatic stability, rapid clearance by reticuloendothelial organs, unwanted stimulation of the immune system, and coagulopathies, limit their application as therapeutics. Many of these side effects are initiated via speci...
| Published: |
|
|---|---|
| Online Access: | http://hdl.handle.net/2047/D20248892 |