Contribution of distal residues in Escherichia coli DinB and human DNA polymerase κ to their activities in translesion synthesis

Contribution of distal residues in Escherichia coli DinB and human DNA polymerase κ to their activities in translesion synthesis

DNA is constantly threatened by damage from endogenous and exogenous sources. Replicative DNA polymerases are typically unable to replicate damaged DNA, but specialized DNA polymerases in the Y family possess this ability. Escherichia coli has two Y family polymerases that are specialized to bypass...

Full description

Bibliographic Details
Published:
Online Access:	http://hdl.handle.net/2047/D20413927

Similar Items

DNA damage specificity of Escherichia coli DNA polymerase DinB
Published: ()

Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine
by: Masaki Hori, et al.
Published: (2010-01-01)

A Genetic Selection for dinB Mutants Reveals an Interaction between DNA Polymerase IV and the Replicative Polymerase That Is Required for Translesion Synthesis.
by: Michelle K Scotland, et al.
Published: (2015-09-01)

Specificity of damage-bypass DNA polymerases E. coli DinB and human pol κ
Published: ()

Features of the Escherichia coli DinB multi-protein complex and the mechanisms by which it regulates DinB's structure and fidelity
Published: ()

Engineering Escherichia coli DNA polymerase III α for translesion synthesis
Published: ()

A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ.
by: Kinrin Yamanaka, et al.
Published: (2012-01-01)

DNA Polymerases ImuC and DinB Are Involved in DNA Alkylation Damage Tolerance in Pseudomonas aeruginosa and Pseudomonas putida.
by: Tatjana Jatsenko, et al.
Published: (2017-01-01)

DinB-RecA interaction is central to Escherichia coli's balance of genomic stability and adaptability through mutagenesis
Published: ()

TRANSLESION DNA POLYMERASES AND CANCER
by: Nick eMakridakis, et al.
Published: (2012-09-01)

A DinB variant reveals diverse physiological consequences of incomplete extension by a Y-family DNA polymerase
by: Jarosz, Daniel F., et al.
Published: (2011)

Translesion Synthesis: Insights into the Selection and Switching of DNA Polymerases
by: Linlin Zhao, et al.
Published: (2017-01-01)

A DinB variant reveals diverse physiological consequences of incomplete TLS extension by a Y-family DNA polymerase
by: Walker, Graham C., et al.
Published: (2011)

Discovery of a DNA damage response in Acinetobacter baumannii and analysis of translesion synthesis DNA polymerases of both A. baumannii and Escherichia coli
Published: ()

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ
by: Tsuda, Masataka
Published: (2017)

Structure and function of the disordered regions within translesion synthesis DNA polymerases
by: Powers, Kyle Thomas
Published: (2018)

Dual roles for DNA polymerase η in homologous DNA recombination and translesion DNA synthesis
by: Araki, Kasumi
Published: (2011)

Translesion Synthesis Polymerases in the Prevention and Promotion of Carcinogenesis
by: L. Jay Stallons, et al.
Published: (2010-01-01)

A chemical genetics analysis of the roles of bypass polymerase DinB and DNA repair protein AlkB in processing N2-alkylguanine lesions in vivo.
by: Nidhi Shrivastav, et al.
Published: (2014-01-01)

Translesion DNA polymerases and genome maintenance in Trypanosoma brucei
by: Zurita Leal, Andrea Cristina
Published: (2017)

Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery
by: Peter Tonzi, et al.
Published: (2018-11-01)

Role of Translesion Synthesis DNA Polymerases in DNA Replication in the Presence of a Weak DNA Polymerase δ in Saccharomyces cerevisiae
by: Likui Zhang, et al.
Published: (2018-02-01)

MsDpo4—a DinB Homolog from Mycobacterium smegmatis—Is an Error-Prone DNA Polymerase That Can Promote G:T and T:G Mismatches
by: Amit Sharma, et al.
Published: (2012-01-01)

A Chemical Genetics Analysis of the Roles of Bypass Polymerase DinB and DNA Repair Protein AlkB in Processing N[superscript 2]-Alkylguanine Lesions In Vivo
by: Shrivastav, Nidhi, et al.
Published: (2014)

Division of labor of Y-family polymerases in translesion-DNA synthesis for distinct types of DNA damage.
by: Yuriko Inomata, et al.
Published: (2021-01-01)

Probing the Base Stacking Contributions During Translesion DNA Synthesis
by: Devadoss, Babho
Published: (2008)

Polymerase exchange on single DNA molecules reveals processivity clamp control of translesion synthesis
by: Kath, James E., et al.
Published: (2014)

Expression and mutational analysis of DinB-like protein DR0053 in Deinococcus radiodurans.
by: Deepti Appukuttan, et al.
Published: (2015-01-01)

The regulation of translesion synthesis through the binding and activation of polymerases by PCNA
by: Boehm, Elizabeth Marie
Published: (2016)

Epistatic roles for Pseudomonas aeruginosa MutS and DinB (DNA Pol IV) in coping with reactive oxygen species-induced DNA damage.
by: Laurie H Sanders, et al.
Published: (2011-04-01)

Architecture of Y-Family DNA Polymerases Relevant to Translesion DNA Synthesis as Revealed in Structural and Molecular Modeling Studies
by: Sushil Chandani, et al.
Published: (2010-01-01)

Computational Evaluation of Nucleotide Insertion Opposite Expanded and Widened DNA by the Translesion Synthesis Polymerase Dpo4
by: Laura Albrecht, et al.
Published: (2016-06-01)

Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress
by: Domenico Maiorano, et al.
Published: (2021-04-01)

Effect of a Monofunctional Phenanthriplatin-DNA Adduct on RNA Polymerase II Transcriptional Fidelity and Translesion Synthesis
by: Kellinger, Matthew W., et al.
Published: (2014)

Proteasomal regulation of the mutagenic translesion DNA polymerase, Saccharomyces cerevisiae Rev1
by: Wiltrout, Mary Ellen, et al.
Published: (2015)

Translesion DNA synthesis in the context of cancer research
by: Knobel Philip A, et al.
Published: (2011-11-01)

Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
by: Ignacio Soriano, et al.
Published: (2021-07-01)

Y-family DNA polymerases in Escherichia coli
by: Jarosz, Daniel F., et al.
Published: (2012)

A Study of Mutagenesis by Translesion Synthesis DNA Polymerases Using A Novel High-throughput Mutation Assay System
by: Chen, Yizhang
Published: (2018)

Thermodynamic Insights by Microscale Thermophoresis into Translesion DNA Synthesis Catalyzed by DNA Polymerases across a Lesion of Antitumor Platinum–Acridine Complex
by: Monika Hreusova, et al.
Published: (2020-10-01)