Synthesis of Trypanosoma cruzi lanosterol 14α demethylase (TcCYP51) inhibitors for the treatment of Chagas disease
Chagas is labeled as a neglected tropical disease (NTD) and has had no successful new drugs in the past 30 years. The current available drugs for treatment of Chagas disease, benznidazole and nifurtimox, have proven to be largely ineffective for chronic stages of the disease, and have significant si...
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| Online Access: | http://hdl.handle.net/2047/d20004887 |