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ndltd-NEU--neu-782
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oai_dc
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ndltd-NEU--neu-7822021-05-26T05:10:40Zsynthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domainsEnsemble Therapeutics, a biotechnology company in Cambridge, MA, bases its research on a new class of compounds known as Ensemblins. Ensemblins are synthetically engineered macrocycles that lie within the structural gap between small-molecule drugs and biological drugs. Ensemblins possess the biophysical properties of small-molecule drugs but the unique macrocyclic structure of Ensemblins allows for high levels of affinity and specificity for targets that are currently only addressable with biological drugs. Ensemble Therapeutics utilizes a technology known as DNA-programmed chemistry to efficiently synthesize large, diverse libraries of Ensemblins.http://hdl.handle.net/2047/d20002533
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NDLTD
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NDLTD
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| description |
Ensemble Therapeutics, a biotechnology company in Cambridge, MA, bases its research on a new class of compounds known as Ensemblins. Ensemblins are synthetically engineered macrocycles that lie within the structural gap between small-molecule drugs and biological drugs. Ensemblins possess the biophysical properties of small-molecule drugs but the unique macrocyclic structure of Ensemblins allows for high levels of affinity and specificity for targets that are currently only
addressable with biological drugs. Ensemble Therapeutics utilizes a technology known as DNA-programmed chemistry to efficiently synthesize large, diverse libraries of Ensemblins.
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| title |
synthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domains
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| spellingShingle |
synthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domains
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| title_short |
synthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domains
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| title_full |
synthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domains
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| title_fullStr |
synthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domains
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| title_full_unstemmed |
synthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domains
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| title_sort |
synthesis of novel synthetic macrocycles containing both peptidic and polyketide-like domains
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| publishDate |
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| url |
http://hdl.handle.net/2047/d20002533
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1719406421769977856
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