Zebrafish bloodthirsty: developmental expression and identification of the Mammalian ortholog.
Blood disorders, such as anemias, are serious diseases in humans. Because the hematopoietic program is highly conserved among vertebrates, we are using fish models to isolate novel erythropoietic genes and to elucidate the functions of the encoded proteins. In this thesis, I describe experiments to...
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| Online Access: | http://hdl.handle.net/2047/d20002114 |
| Summary: | Blood disorders, such as anemias, are serious diseases in humans. Because the hematopoietic program is highly conserved among vertebrates, we are using fish models to isolate novel erythropoietic genes and to elucidate the functions of the encoded proteins. In this thesis, I describe experiments to examine the developmental expression patterns of the novel zebrafish gene, bloodthirsty (bty), and to identify its probable mammalian ortholog. |
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