Discovery of unknown modifications in recombinant monoclonal antibodies

Discovery of unknown modifications in recombinant monoclonal antibodies

Recombinant monoclonal antibodies have become one of the most important classes of biotherapeutics today. Due to their complexity, they must be produced by cellular expression. They are subject to various posttranslational modifications during manufacture, formulation and storage. Occasionally, the...

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Online Access:	http://hdl.handle.net/2047/d20128879

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