Coupled dynamics of voltage and calcium in paced cardiac cells

We investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret vari...

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Online Access:http://hdl.handle.net/2047/d20000436
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spelling ndltd-NEU--neu-3321942016-04-25T16:14:51ZCoupled dynamics of voltage and calcium in paced cardiac cellsWe investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret various experimentally observed modes of instability ranging from electromechanically concordant and discordant alternans to quasiperiodic oscillations of voltage and calcium.http://hdl.handle.net/2047/d20000436
collection NDLTD
sources NDLTD
description We investigate numerically and analytically the coupled dynamics of transmembrane voltage and intracellular calcium cycling in paced cardiac cells using a detailed physiological model and its reduction to a three-dimensional discrete map. The results provide a theoretical framework to interpret various experimentally observed modes of instability ranging from electromechanically concordant and discordant alternans to quasiperiodic oscillations of voltage and calcium.
title Coupled dynamics of voltage and calcium in paced cardiac cells
spellingShingle Coupled dynamics of voltage and calcium in paced cardiac cells
title_short Coupled dynamics of voltage and calcium in paced cardiac cells
title_full Coupled dynamics of voltage and calcium in paced cardiac cells
title_fullStr Coupled dynamics of voltage and calcium in paced cardiac cells
title_full_unstemmed Coupled dynamics of voltage and calcium in paced cardiac cells
title_sort coupled dynamics of voltage and calcium in paced cardiac cells
publishDate
url http://hdl.handle.net/2047/d20000436
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