Cysteine dependence of insulin-like growth factor effects on redox and methylation status

Methionine synthase serves as a bridge between the methionine cycle and the dopamine-stimulated phospholipid methylation cycle. Cobalamin is the co-factor of methionine synthase to catalyze the conversion of homocysteine to methionine. Oxidized cobalamin halts methionine synthase activity, increasin...

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Online Access:http://hdl.handle.net/2047/d20002964
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spelling ndltd-NEU--neu-17792021-05-25T05:10:13ZCysteine dependence of insulin-like growth factor effects on redox and methylation statusMethionine synthase serves as a bridge between the methionine cycle and the dopamine-stimulated phospholipid methylation cycle. Cobalamin is the co-factor of methionine synthase to catalyze the conversion of homocysteine to methionine. Oxidized cobalamin halts methionine synthase activity, increasing homocysteine diversion to the transsulfuration pathway leading to formation of cysteine which can then be converted to the primary intracellular antioxidant glutathione.http://hdl.handle.net/2047/d20002964
collection NDLTD
sources NDLTD
description Methionine synthase serves as a bridge between the methionine cycle and the dopamine-stimulated phospholipid methylation cycle. Cobalamin is the co-factor of methionine synthase to catalyze the conversion of homocysteine to methionine. Oxidized cobalamin halts methionine synthase activity, increasing homocysteine diversion to the transsulfuration pathway leading to formation of cysteine which can then be converted to the primary intracellular antioxidant glutathione.
title Cysteine dependence of insulin-like growth factor effects on redox and methylation status
spellingShingle Cysteine dependence of insulin-like growth factor effects on redox and methylation status
title_short Cysteine dependence of insulin-like growth factor effects on redox and methylation status
title_full Cysteine dependence of insulin-like growth factor effects on redox and methylation status
title_fullStr Cysteine dependence of insulin-like growth factor effects on redox and methylation status
title_full_unstemmed Cysteine dependence of insulin-like growth factor effects on redox and methylation status
title_sort cysteine dependence of insulin-like growth factor effects on redox and methylation status
publishDate
url http://hdl.handle.net/2047/d20002964
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