Enhancement of in vitro therapeutic efficacy using combination paclitaxel and ceramide therapy using EGFR targeted biodegradable polymeric nanoparticles in ovarian cancer model
Currently, tumor-cell resistance to the chemotherapy is key reason for failure of the clinical treatment of cancer cells; almost all chemotherapeutic strategies used are susceptible to multidrug resistance (MDR). The development of MDR is major hindrance to eradication of cancer as it interferes wit...
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| Online Access: | http://hdl.handle.net/2047/d20002956 |
| Summary: | Currently, tumor-cell resistance to the chemotherapy is key reason for failure of the clinical treatment of cancer cells; almost all chemotherapeutic strategies used are susceptible to multidrug resistance (MDR). The development of MDR is major hindrance to eradication of cancer as it interferes with the effect of therapeutic agents on tumors and increases chances of cancer resurgence. |
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