novel self-sensing piezoelectric microcantilever-based sensor for detection of ultrasmall masses and biological species

Nanotechnological advancements have made great contributions in developing label-free and highly sensitive biosensors. Development of biosensing tools has contributed significantly to high-throughput diagnosis and analytical sensing exploiting high affinity of biomolecules. Detection of ultrasmall a...

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Online Access:http://hdl.handle.net/2047/d20003322
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Summary:Nanotechnological advancements have made great contributions in developing label-free and highly sensitive biosensors. Development of biosensing tools has contributed significantly to high-throughput diagnosis and analytical sensing exploiting high affinity of biomolecules. Detection of ultrasmall adsorbed masses has been enabled by such sensors which translate molecular interaction into detectable physical quantities. More specifically microcantilever (MC)-based biosensors have caught a widespread attention for offering label-free, highly sensitive, and inexpensive platform for detection. MC-based systems with different applications are equipped with external devices and instruments for actuation and read-out purposes which makes the entire platform expensive and bulky. Although there have been a number of measurement techniques, a compact detection platform with the capability of miniaturization, low power consumption, cost effective, and yet sensitive methodology is highly desirable.