Temperature-induced unfolding, aggregation, and interaction of therapeutic monoclonal antibodies

Temperature-induced unfolding, aggregation, and interaction of therapeutic monoclonal antibodies

Bibliographic Details
Main Author:	Menzen, Tim Andreas
Format:	Others
Published:	Ludwig-Maximilians-Universität München 2014
Subjects:	Fakultät für Chemie und Pharmazie
Online Access:	http://edoc.ub.uni-muenchen.de/17520/1/Menzen_Tim_Andreas.pdf http://nbn-resolving.de/urn:nbn:de:bvb:19-175200

Similar Items

Aggregation of therapeutic antibodies in the course of downstream processing
by: Rosenberg, Eva
Published: (2010)

Inhibition of therapeutic protein aggregation by cyclodextrins
by: Serno, Tim
Published: (2010)

Crystalline Monoclonal Antibodies: Development of stable crystals for drying and sustained release formulations
by: Hildebrandt, Christian
Published: (2014)

Development of sustained release formulations for the intra-articular delivery of a therapeutic antibody
by: Ruberg, Eva-Maria
Published: (2013)

Unfolding and compaction in chaperonin-assisted protein folding followed by single molecule and ensemble FRET
by: Sharma, Shruti
Published: (2007)

Organocuprate aggregation and reactivity
by: Putau, Aliaksei
Published: (2012)

The immunogenicity of protein aggregates
by: Freitag, Angelika Juliane
Published: (2012)

Antibodies directed against the 37 kDa/67 kDa laminin receptor as therapeutic tools for the treatment of prion diseases and cancer
by: Zuber, Chantal
Published: (2008)

Genetic engineering of adenoviral vectors for improved therapeutic applications
by: Mück-Häusl, Martin Andreas
Published: (2011)

Aggregation of Organozinc Species in Solution and Their Reactivity
by: Fleckenstein, Julia Elisabeth
Published: (2011)

Influence of the antibody variable domain on FcRn-dependent pharmacokinetics
by: Schoch, Angela
Published: (2014)

Involvement of latent TGF-beta binding protein 1 in CADASIL-relevant Notch3 aggregation
by: Kast, Jessica
Published: (2014)

Pharmacokinetic profiling of therapeutic proteins and variants by mass spectrometry
by: Higel, Fabian Benjamin
Published: (2014)

Molekulare Analyse der Huntingtin-Aggregation und deren Modulation durch das eukaryontische Chaperonin TRiC
by: Langer, Carola Alexandra
Published: (2007)

Subcutaneous suspensions of therapeutic proteins formulated as protein-coated microcrystals
by: Berkenhoff, Kristine
Published: (2013)

New analytical methods for the assessment of the physical stability of therapeutical proteins
by: Spalthoff, Veronika Maria
Published: (2013)

Novel approaches for stabilization and characterization of therapeutic proteins in liquid formulations
by: Härtl, Elisabeth
Published: (2013)

Role of the Hep1 chaperone in the de novo folding and the prevention of aggregation of the mitochondrial Hsp70 chaperone Ssc1
by: Blamowska, Marta
Published: (2012)

Cell culture models and novel gene therapeutic strategies for colorectal cancer
by: Gaedtke, Lars
Published: (2006)

Single chain antibodies against the 37 kDa/67 kDa laminin receptor as tools for prion diseases therapy
by: Rey, Clémence
Published: (2006)

High-Temperature Superconductivity in Doped BaFe2As2
by: Martin, Marianne
Published: (2011)

Statistical methods for the inference of interaction networks
by: Dümcke, Sebastian
Published: (2014)

Interaction studies of the cellular prion protein
by: Hundt, Christoph
Published: (2002)

Correlation of structure and performance in high temperature polymer electrolyte membrane fuel cells
by: Heinzl, Christoph
Published: (2014)

Scalable quantitative interaction proteomics of regulatory DNA elements
by: Viturawong, Thanatip
Published: (2014)

Untersuchungen zum Replikationsverhalten carbozyklischer Analoga der Formamidopyrimidine des 2´-Desoxyadenosin und 2´-Desoxyguanosin
by: Gehrke, Tim
Published: (2012)

The role of integrins and cytoskeletal forces in interstitial leukocyte migration
by: Lämmermann, Tim
Published: (2009)

Lipophile fluoreszierende Nanostrukturen in hydrophiler Phase
by: Pust, Tim
Published: (2009)

Structure, dynamics and interactions in porous host-guest systems
by: Rühle, Bastian
Published: (2013)

Preparation of New Functionalized Organomagnesium Reagents using a Low Temperature Halogen-Magnesium Exchange
by: Vu, Viet Anh
Published: (2003)

Iron based superconductors and related compounds synthesized by solid state metathesis and high temperature reactions
by: Frankovsky, Rainer
Published: (2013)

Triazolobenzodiazepines and -triazepines as protein interaction inhibitors targeting bromodomains of the BET family
by: Wrobel, Matthias
Published: (2014)

Analysis of Adenovirus-Host Interactions to Improve Recombinant Adenoviral Vectors for Gene Therapy
by: Rauschhuber, Christina
Published: (2011)

Live-cell imaging elucidates cellular interactions of gene nanocarriers for cancer therapy
by: Mickler, Frauke Martina
Published: (2013)

Structural characterization of the Timeless-Tipin-RPA Complex and its interaction with ssDNA
by: Witosch, Justine Martha
Published: (2015)

Analysis of TF interactions with ribosome-nascent chain complexes-photocrosslinking and fluorescence spectroscopic approaches
by: Lakshmipathy, Sathish Kumar
Published: (2009)

Characterization of the Cyclin Dependent Kinase Complex Bur1-2 and its Interaction with RPA
by: Clausing, Emanuel
Published: (2008)

Genome wide recruitment of TREX reveals a direct interaction with the Rpb1 CTD
by: Meinel, Dominik
Published: (2013)

Functional characterization of PINCH-1 in embryoid bodies and keratinocytes and identification of new interaction partners
by: Karaköse, Esra
Published: (2012)

The Significance of FRS2 Phosphorylation in EGF- and FGF-Induced Signaling
by: Wu, Yingjie
Published: (2003)