Characterization of murine pancreatic carcinoma models regarding immunosuppressive mechanisms and therapy with bifunctional siRNA targeting galectin-1
Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive tumor that is characterized by abundant tumor stroma and a potent immunosuppressive microenvironment. Further studies to clarify why T cells infiltrate the tumor but are not able to perform effector functions as well as to find new effecti...
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Ludwig-Maximilians-Universität München
2014
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Online Access: | http://edoc.ub.uni-muenchen.de/17449/1/Adunka_Tina.pdf http://nbn-resolving.de/urn:nbn:de:bvb:19-174491 |