Structural and biochemical characterization of eukaryotic mRNA decapping activators
In eukaryotes, mRNA turnover starts with the truncation of 3′ poly(A) tail and proceeds with either 3′-to-5′ degradation by the exosome complex or with decapping followed by 5′-to-3′ degradation by Xrn1. mRNA decapping is catalyzed by the decapping enzyme complex Dcp1-Dcp2 and is regulated by a high...
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Ludwig-Maximilians-Universität München
2014
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| Online Access: | http://edoc.ub.uni-muenchen.de/17300/1/Sharif_Humayun.pdf http://nbn-resolving.de/urn:nbn:de:bvb:19-173006 |