Investigations of the inhibition mechanisms of human ribonucleotide reductase by gemcitabine-5'-diphosphate and saccharomyces cerevisiae ribonucleotide reductase by Sml1

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 2009. === Vita. Cataloged from PDF version of thesis. === Includes bibliographical references. === Ribonucleotide reductases (RNRs) catalyze the conversion of nucleotides to deoxynucleotides supplying the dNTPs required for...

Full description

Bibliographic Details
Main Author: Wang, Jun, Ph. D. Massachusetts Institute of Technology
Other Authors: JoAnne Stubbe.
Format: Others
Language:English
Published: Massachusetts Institute of Technology 2010
Subjects:
Online Access:http://hdl.handle.net/1721.1/55099