Studies on the total synthesis of gymnocin B
Thesis: Ph. D. in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, 2017. === Cataloged from PDF version of thesis. === Includes bibliographical references. === Progress toward the biomimetic total synthesis of gymnocin B is described. Synthesis of the ABCDEFGH fragm...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Others |
| Language: | English |
| Published: |
Massachusetts Institute of Technology
2017
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/1721.1/112442 |
| Summary: | Thesis: Ph. D. in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, 2017. === Cataloged from PDF version of thesis. === Includes bibliographical references. === Progress toward the biomimetic total synthesis of gymnocin B is described. Synthesis of the ABCDEFGH fragment has been completed in 30 steps longest linear sequence, using three different types of epoxide-opening cascades and one fragment coupling. Synthesis of the KLMNO fragment has been completed in 27 steps longest linear sequence, using one epoxide-opening cascade and one fragment coupling. The completion plan of gymnocin B is also detailed. [chemical formulas] === by Satapanawat Sittihan. === Ph. D. in Organic Chemistry |
|---|