c-Myc dependent genomic instability of the ribonucleotide reductase R2 gene
c-Myc deregulation has been shown to generate locus-specific chromosomal and extrachromosomal gene amplification, as well as karyotypic instability. My studies focused on c-Myc-dependent amplification of a new c-Myc amplification target, the 'ribonucleotide reductase R2' gene. Using a mou...
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| Language: | en_US |
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2007
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| Online Access: | http://hdl.handle.net/1993/1748 |