Reductive 17beta-hydroxysteroid dehydrogenase types 1, 5 and 7 involved in hormone-dependent cancers : 3D-structure, function and inhibition
La famille des enzymes 17β-hydroxystéroïde déshydrogénases (17β-HSDs) humaines est responsable de la biosynthèse des hormones stéroïdiennes. Les enzymes réductrices de cette famille, c'est-à-dire la 17β-HSDl, la 17β-HSD5 et la 17β-HSD7, sont impliquées dans la dernière étape de la synthèse des...
Main Author: | Mazumdar, Mausumi |
---|---|
Other Authors: | Lin, Sheng-Xiang |
Format: | Doctoral Thesis |
Language: | English |
Published: |
Université Laval
2010
|
Subjects: | |
Online Access: | http://hdl.handle.net/20.500.11794/21931 |
Similar Items
-
Expression and role of 17BETA-hydroxysteroid dehydrogenase type 1, 5 and 7 in epithelial ovarian cancer
by: Wang, Ruixuan
Published: (2018) -
Role of 17β-hydroxysteroid dehydrogenase type 5 in breast cancer studied by intracrinology
by: Xu, Dan (Ph.D)
Published: (2015) -
Function and regulation of 17B-hydroxysteroid dehydrogenase type7 (17B-HSD7) in sex hormone biosynthesis and breast cancer : in vitro, in vivo, proteomic and three dimensional co-culture studies
by: Wang, Xiao Qiang
Published: (2015) -
Structure and biological function of human 3-alpha hydroxysteroid dehydrogenase type 3 in breast cancer
by: Zhang, Bo
Published: (2014) -
Substrate inhibition of 17 beta-hydroxysteroid dehydrogenase type 1 in living cells and regulation among the steroid-converting enzymes in breast cancers
by: Han, Hui
Published: (2018)