The effects of administration of a nuclear factor kappa-B inhibitor on pulmonary endothelial dysfunction after cardiopulmonary bypass: impact on oxygenation and hemodynamics and development of therapeutic and preventive modalities in a porcine model

The effects of administration of a nuclear factor kappa-B inhibitor on pulmonary endothelial dysfunction after cardiopulmonary bypass: impact on oxygenation and hemodynamics and development of therapeutic and preventive modalities in a porcine model

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Introduction: La circulation extracorporelle (CEC) peut entraîner une dysfonction endothéliale pulmonaire et l’hypertension pulmonaire. Le SN50 agit au niveau de la signalisation cellulaire pour prévenir ces réactions à la CEC et pourrait renverser la dysfonction endothéliale pulmonaire post-CEC san...

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Bibliographic Details
Main Author: Rosu, Cristian
Other Authors: Perrault, Louis
Language:en
Published: 2014
Subjects:
Endothelial dysfunction
Cardiopulmonary bypass
Pulmonary hypertension
Nuclear factor kappa-B
Phosphodiesterase inhibitors
Dysfonction endothéliale
Hypertension pulmonaire
Circulation extracorporelle
Facteur nucléaire kappa-B
Inhibiteurs de la phosphodiestérase
Biology - Physiology / Biologie - Physiologie (UMI : 0719)
Online Access:http://hdl.handle.net/1866/10590

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