A curated database and probabilistic model of endoplasmic reticulum quality control /
The folding and assembly of proteins in the endoplasmic reticulum (ER) lumen and membrane are monitored by ER quality control (ERQC) mechanisms. This thesis focuses on two elements of ERQC: the unfolded protein response (UPR) and ER-associated degradation (ERAD), essential processes that prevent the...
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Format: | Others |
Language: | en |
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McGill University
2005
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=97917 |