Biochemical basis for a genetically determined difference in response to the teratogenic effects of 6-amino-nicotinamide.

The application of precisely timed, short exposures of embryos to specific metabolic inbibitors is a useful method for analysing the biochemical aspects of development. The teratologic approach to the study of the biochemical requirerments of various organogenetic processes in the developing embryo...

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Bibliographic Details
Main Author: Verrusio, A. Carl
Other Authors: Fraser, F. (Supervisor)
Format: Others
Language:en
Published: McGill University 1966
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=73627
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Summary:The application of precisely timed, short exposures of embryos to specific metabolic inbibitors is a useful method for analysing the biochemical aspects of development. The teratologic approach to the study of the biochemical requirerments of various organogenetic processes in the developing embryo was first formulated by Warkany (1944) who showed that the offspring of female rats maintained on a vitamin A deficient diet had characteristic patterns of malformations. [...]