The synthesis of methyl trihydroxyeicosatrienoates and related compounds /

Efficient syntheses for appropriately derivatized methyl 8R,9(R and S), 11R-trihydroxy-12-oxododeca-5Z-enoates (53, 59) via their respective 5,6-anhydro-3-deoxy-1,2-0-isopropylidene-(alpha)-D-hexofuranoses (18 and 38) are described. These aldehydes were subsequently converted to the corresponding me...

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Main Author:	Luthe, Corinne Elizabeth.
Format:	Others
Language:	en
Published:	McGill University 1981
Subjects:	Methyl groups.
Online Access:	http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=68571

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spelling	ndltd-LACETR-oai-collectionscanada.gc.ca-QMM.685712014-02-13T04:08:15ZThe synthesis of methyl trihydroxyeicosatrienoates and related compounds /Luthe, Corinne Elizabeth.Methyl groups.Efficient syntheses for appropriately derivatized methyl 8R,9(R and S), 11R-trihydroxy-12-oxododeca-5Z-enoates (53, 59) via their respective 5,6-anhydro-3-deoxy-1,2-0-isopropylidene-(alpha)-D-hexofuranoses (18 and 38) are described. These aldehydes were subsequently converted to the corresponding methyl 8(R and S), 9(R and S), 11R-trihydroxy-eicosa-5Z,12E,14Z-trienoates (64, 72, 82, 91). Model studies towards the synthesis of 8R,11R,15(R and S)-trihydroxy-9S,12-oxyeicosa-5Z,13E-dienoic acids (1) were carried out.McGill University1981Electronic Thesis or Dissertationapplication/pdfenalephsysno: 000114589proquestno: AAINK52022Theses scanned by UMI/ProQuest.All items in eScholarship@McGill are protected by copyright with all rights reserved unless otherwise indicated.Doctor of Philosophy (Department of Chemistry) http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=68571
collection	NDLTD
language	en
format	Others
sources	NDLTD
topic	Methyl groups.
spellingShingle	Methyl groups. Luthe, Corinne Elizabeth. The synthesis of methyl trihydroxyeicosatrienoates and related compounds /
description	Efficient syntheses for appropriately derivatized methyl 8R,9(R and S), 11R-trihydroxy-12-oxododeca-5Z-enoates (53, 59) via their respective 5,6-anhydro-3-deoxy-1,2-0-isopropylidene-(alpha)-D-hexofuranoses (18 and 38) are described. These aldehydes were subsequently converted to the corresponding methyl 8(R and S), 9(R and S), 11R-trihydroxy-eicosa-5Z,12E,14Z-trienoates (64, 72, 82, 91). Model studies towards the synthesis of 8R,11R,15(R and S)-trihydroxy-9S,12-oxyeicosa-5Z,13E-dienoic acids (1) were carried out.
author	Luthe, Corinne Elizabeth.
author_facet	Luthe, Corinne Elizabeth.
author_sort	Luthe, Corinne Elizabeth.
title	The synthesis of methyl trihydroxyeicosatrienoates and related compounds /
title_short	The synthesis of methyl trihydroxyeicosatrienoates and related compounds /
title_full	The synthesis of methyl trihydroxyeicosatrienoates and related compounds /
title_fullStr	The synthesis of methyl trihydroxyeicosatrienoates and related compounds /
title_full_unstemmed	The synthesis of methyl trihydroxyeicosatrienoates and related compounds /
title_sort	synthesis of methyl trihydroxyeicosatrienoates and related compounds /
publisher	McGill University
publishDate	1981
url	http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=68571
work_keys_str_mv	AT luthecorinneelizabeth thesynthesisofmethyltrihydroxyeicosatrienoatesandrelatedcompounds AT luthecorinneelizabeth synthesisofmethyltrihydroxyeicosatrienoatesandrelatedcompounds
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The synthesis of methyl trihydroxyeicosatrienoates and related compounds /

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