Trolox enhances anti-leukemic effects of arsenic trioxide: the role of oxidative stress
Arsenic trioxide (As2O3) has considerable efficacy in the treatment of acute promyelocytic leukemia (APL), inducing partial differentiation and promoting apoptosis of malignant promyelocytes. Although initial studies focused on the role of the characteristic APL fusion protein, PML-RARα, in mediatin...
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| Format: | Others |
| Language: | en |
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McGill University
2009
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=40699 |