Enzyme substitution therapy for hyperphenylalaninemia with phenylalanine ammonia lyase : an alternative to low phenylalanine dietaty treatment : effective in mouse models
Phenylketonuria (PKU) and related forms of non-PKU hyperphenylalaninemias (HPA) result from deficiencies in phenylalanine hydroxylase (PAH), the hepatic enzyme that catalyses the conversion of phenylalanine (phe) to tyrosine (tyr). Patients are characterised by a metabolic phenotype comprising eleva...
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| Format: | Others |
| Language: | en |
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McGill University
2000
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37832 |