Trans-dominant negative inhibition of human immunodeficiency virus type 1 replication by expression of protease-reverse transcriptase fusion proteins
The molecular mechanisms involved in the regulation of protease (PR) activity and human immunodeficiency virus type 1 (HIV-1) viral maturation are incompletely elucidated. To better understand the importance of the cleavage event between HIV-1 PR and reverse transcriptase (RT), we have selectively m...
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Format: | Others |
Language: | en |
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McGill University
1999
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=35840 |