Modulation of endothelial cell survival by the angiopoietin-1Tie-2 receptor pathway
The mechanisms by which Angiopoietin-1 (Ang-1) modulates the survival of human endothelial cells were investigated. Ang-1 inhibited both TNFalpha-induced and serum deprivation-evoked apoptosis, an effect which was associated with attenuation of caspase activation, inhibition of Smac release from the...
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Format: | Others |
Language: | en |
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McGill University
2002
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Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33771 |