Modulation of endothelial cell survival by the angiopoietin-1Tie-2 receptor pathway

The mechanisms by which Angiopoietin-1 (Ang-1) modulates the survival of human endothelial cells were investigated. Ang-1 inhibited both TNFalpha-induced and serum deprivation-evoked apoptosis, an effect which was associated with attenuation of caspase activation, inhibition of Smac release from the...

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Bibliographic Details
Main Author: Harfouche, Rania.
Other Authors: Dhindsa, R. (advisor)
Format: Others
Language:en
Published: McGill University 2002
Subjects:
Online Access:http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33771