The inheritance of loss: Caspase-6 activity and effect in human neurons caused by familial Alzheimer's Disease associated mutants
Active Caspase 6 associates with the neuropathological hallmarks of sporadic Alzheimer disease (SAD), indirectly increases amyloid beta (A-Beta) and cleaves Tau and other cytoskeleton proteins. Given the similar neuropathology of SAD and familial AD (FAD)...
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| Format: | Others |
| Language: | en |
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McGill University
2009
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| Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32417 |