Synthesis and gene silencing activity of ribonucleic acid duplexes containing 3'-deoxy-3'-thiothymidine
This thesis reports the first synthesis and biophysical characterization of oligoribonucleotides (RNA) containing 3'-deoxy-3'-thiothymidine (3'-S-dT) units. Optimized conditions for incorporating 3'-S-dT into 21-nt RNA strands is also...
Main Author: | Isaac, Siara |
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Other Authors: | Masad J Damha (Internal/Supervisor) |
Format: | Others |
Language: | en |
Published: |
McGill University
2009
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Subjects: | |
Online Access: | http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=32408 |
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